Uses of Dornase Alfa: It is used to lower the number of lung infections and help lung function in cystic fibrosis. If you have an allergy to dornase alfa or any other part of dornase alfa. If you are allergic to hamsters, talk with the doctor. If you are allergic to dornase alfa; any part of dornase alfa; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
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Read them carefully before using the medicine. If you do not understand the directions or you are not sure how to use the nebulizer, ask your doctor to show you how to use it.
Use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.
Also, do not stop using this medicine without telling your doctor. To do so may cause your lung condition to become worse. To use: Dornase alfa inhalation solution comes in small plastic containers called ampules.
Each ampule contains one full dose of dornase alfa. Do not use an ampule that has already been opened. An air compressor is used with a nebulizer to turn the medicine into a fine spray. You will breathe in the spray through your mouth. Do not use a face mask with the nebulizer because less medicine will get into your lungs. Make sure you understand exactly how to use this medicine in the nebulizer. Do not use a cloudy or discolored inhalation solution. You will need to use the nebulizer for about 10 to 15 minutes, or until the medicine in the nebulizer cup is gone.
In order to receive the full effects of this medicine, you must use it every day as ordered by your doctor. If possible, dornase alfa should be used at about the same time each day. You may notice some improvement in your condition within the first week of treatment.
However, some patients may not feel the full effects of this medicine for weeks or months. If you are taking any other medicines for cystic fibrosis, keep taking them as you did before you started using dornase alfa, unless otherwise directed by your doctor. However, do not put any other inhaled medicine in the nebulizer at the same time that you use dornase alfa.
Other inhaled medicines may be used in a clean nebulizer before or after your treatment with dornase alfa. Dosing The dose of this medicine will be different for different patients.
The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
For inhalation dosage form solution : For cystic fibrosis: Adults and children 5 years of age and older—2. Children 3 months to 4 years of age—Dose must be determined by your doctor. The dose is usually 2. Children younger than 3 months of age—Use and dose must be determined by your doctor.
Missed Dose If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use.
Store the medicine in the refrigerator in the foil pouches. However, keep the medicine from freezing. Do not leave this medicine out of the refrigerator for longer than 24 hours. If an ampule of medicine is left out for longer than this, it should be thrown away and a new ampule should be used.
Precautions Portions of this document last updated: Feb. All rights reserved.
Read them carefully before using the medicine. If you do not understand the directions or you are not sure how to use the nebulizer, ask your doctor to show you how to use it. Use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. Also, do not stop using this medicine without telling your doctor. To do so may cause your lung condition to become worse. To use: Dornase alfa inhalation solution comes in small plastic containers called ampules.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. Back to Top Dornase Alfa Interactions Do not dilute or mix the dornase alfa solution with any other drugs in the nebulizer. Mixing of dornase alfa with other drugs could lead to changes in the actions of the medications.
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